All Publications
Challenges and perspectives of CRISPR-based technology for diagnostic applications
Del Giovane, S., Bagheri, N., Di Pede, AC., Chamorro, A., Ranallo, S., Migliorelli, D., Burr, L., Paoletti, S., Altug, H., Porchetta, A.
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PAM-Engineered Toehold Switches as Input-Responsive Activators of CRISPR-Cas12a for Sensing Applications
Bagheri, N., Chamorro, A., Idili, A., Porchetta, A.
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Supramolecular Nucleic Acid-Based Organosilica Nanoparticles Responsive to Physical and Biological Inputs
Picchetti, P., Volpi, S., Sancho-Albero, M., Rossetti, M., Dore, M. D., Trinh, T., Biedermann, F., Neri, M., Bertucci, A., Porchetta, A., Corradini, R., Sleiman, H., and De Cola, L.
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Responsive Nucleic Acid-Based Organosilica Nanoparticles
Picchetti, Volpi, S., Rossetti, M., Dore, M. D., Trinh, T., Biedermann, F., Neri, M., Bertucci, A., Porchetta, A., Corradini, R., Sleiman, H., and De Cola, L.
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Minimalist Design of Wireframe DNA Nanotubes: Tunable Geometry, Size, Chirality, and Dynamics
Luo, X., Saliba, D., Yang, T., Gentile, S., Mori, K., Islas, P., Das, T., Bagheri, N., Porchetta, A., Guarne, A., Cosa, G. and Sleiman, H.F.
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Enhancement of CRISPR/Cas12a trans-cleavage activity using hairpin DNA reporters
Rossetti, M., Merlo, R., Bagheri, N., Moscone, D., Valenti, A., Saha, A., Arantes, P.R., Ippodrino, R., Ricci, F., Treglia, I., Delibato, E., Van Der Oost, J., Palermo, G., Perugino, G. & Porchetta, A. (2022). Nucleic Acids Research, 50(14), 8377-8391.
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Programmable cell- free transcriptional switches for antibody detection
Patino Diaz, A., Bracaglia, S., Ranallo, S., Patino, T., Porchetta, A., & Ricci, F. (2022). Journal of the American Chemical Society, 144(13), 5820-5826.
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Controlling dynamic DNA reactions at the surface of single-walled carbon nanotube electrodes to design hybridization platforms with a specific amperometric readout
Fortunati, S., Vasini, I., Giannetto, M., Mattarozzi, M., Porchetta, A., Bertucci, A., & Careri, M. (2022). Analytical Chemistry, 94(12), 5075-5083.
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Engineering DNA-grafted quatsomes as stable nucleic acid-responsive fluorescent nanovesicles
Rossetti, M., Stella, L., Morlà-Folch, J., Bobone, S., Boloix, A., Baranda, L., Moscone, D., Roldán, M., Veciana, J., Segura, M.F., Köber, M., Ventosa, N. & Porchetta, A. (2021). Advanced Functional Materials, 31(46).
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DNA- based nanoswitches: Insights into electrochemiluminescence signal enhancement
Zanut, A., Rossetti, M., Marcaccio, M., Ricci, F., Paolucci, F., Porchetta, A., & Valenti, G. (2021). Analytical Chemistry, 93(30), 10397-10402.
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Folding-upon-repair DNA nanoswitches for monitoring the activity of DNA repair enzymes
Farag, N., Mattossovich, R., Merlo, R., Nierzwicki, Ł., Palermo, G., Porchetta, A., Perugino, G. & Ricci, F. (2021). Angewandte Chemie - International Edition, 60(13), 7283-7289.
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Protein-controlled actuation of dynamic nucleic acid networks by using synthetic DNA translators
Bertucci, A., Porchetta, A., Del Grosso, E., Patiño, T., Idili, A., & Ricci, F. (2020). Angewandte Chemie - International Edition, 59(46), 20577-20581.
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Rapid, cost-effective Peptide/Nucleic acid-based platform for therapeutic antibody monitoring in clinical samples
Mocenigo, M., Porchetta, A., Rossetti, M., Brass, E., Tonini, L., Puzzi, L., Tagliabue, E., Triulzi, T., Marini, B., Ricci, F. & Ippodrino, R. (2020). ACS Sensors, 5(10), 3109-3115.
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Harnessing effective molarity to design an electrochemical DNA-based platform for clinically relevant antibody detection
Rossetti, M., Brannetti, S., Mocenigo, M., Marini, B., Ippodrino, R., & Porchetta, A. (2020). Angewandte Chemie - International Edition, 59(35), 14973-14978.
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Programming DNA-based systems through effective molarity enforced by biomolecular confinement
Rossetti, M., Bertucci, A., Patiño, T., Baranda, L., & Porchetta, A. (2020). Chemistry - A European Journal, 26(44), 9826-9834.
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Programmable RNA-based systems for sensing and diagnostic applications
Rossetti, M., Del Grosso, E., Ranallo, S., Mariottini, D., Idili, A., Bertucci, A., & Porchetta, A. (2019). Analytical and Bioanalytical Chemistry, 411(19), 4293-4302.
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Printing life-inspired subcellular scale compartments with autonomous molecularly crowded confinement
Arrabito, G., Cavaleri, F., Porchetta, A., Ricci, F., Vetri, V., Leone, M., & Pignataro, B. (2019). Advanced Biosystems, 3(7).
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Self- sensing enzyme-powered micromotors equipped with pH-responsive DNA nanoswitches
Patino, T., Porchetta, A., Jannasch, A., Lladó, A., Stumpp, T., Schäffer, E., Ricci, F. & Sánchez, S. (2019). Nano Letters, 19(6), 3440-3447.
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Re-modeling ELISA kits embedded in an automated system suitable for on-line detection of algal toxins in seawater
Petropoulos, K., Bodini, S. F., Fabiani, L., Micheli, L., Porchetta, A., Piermarini, S., Volpe, G., Pasquazzi, F.M., Sanfilippo, L., Moscetta, P., Chiavarini, S. & Palleschi, G. (2019). Sensors and Actuators, B: Chemical, 283, 865-872.
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A label-free impedimetric aptasensor for the detection of bacillus anthracis spore simulant
Mazzaracchio, V., Neagu, D., Porchetta, A., Marcoccio, E., Pomponi, A., Faggioni, G., D'Amore, N., Notargiacomo, A., Pea, M.L.I., Moscone, D., Palleschi, G., Lista, F. & Arduini, F. (2019). Biosensors and Bioelectronics, 126, 640-646.
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DNA-based scaffolds for sensing applications
Ranallo, S., Porchetta, A., & Ricci, F. (2019). Analytical Chemistry, 91(1), 44-59.
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Integrated chemiluminescence-based lab-on-chip for detection of life markers in extraterrestrial environments
Nascetti, A., Mirasoli, M., Marchegiani, E., Zangheri, M., Costantini, F., Porchetta, A., Annascoli, L., Lovecchio, N., Caputo, D., de Cesare, G., Pirrotta, S. & Roda, A (2019). Biosensors and Bioelectronics, 123, 195-203.
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Allosterically regulated DNA-based switches: From design to bioanalytical applications
Rossetti, M., & Porchetta, A. (2018). Analytica Chimica Acta, 1012, 30-41.
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Antibody-mediated small molecule detection using programmable DNA-switches
Rossetti, M., Ippodrino, R., Marini, B., Palleschi, G., & Porchetta, A. (2018). Analytical Chemistry, 90(13), 8196-8201.
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Programmable nucleic acid nanoswitches for the rapid, single-step detection of antibodies in bodily fluids
Porchetta, A., Ippodrino, R., Marini, B., Caruso, A., Caccuri, F., & Ricci, F. (2018). Journal of the American Chemical Society, 140(3), 947-953.
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Antibody-templated assembly of an RNA mimic of green fluorescent protein
Bertucci, A., Porchetta, A., & Ricci, F. (2018). Analytical Chemistry, 90(2), 1049-1053.
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Allosteric DNA nanoswitches for controlled release of a molecular cargo triggered by biological inputs
Rossetti, M., Ranallo, S., Idili, A., Palleschi, G., Porchetta, A., & Ricci, F. (2017). Chemical Science, 8(2), 914-920.
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A modular clamp-like mechanism to regulate the activity of nucleic-acid target-responsive nanoswitches with external activators
Del Grosso, E., Idili, A., Porchetta, A., & Ricci, F. (2016). Nanoscale, 8(42), 18057-18061.
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Using nature’s “tricks” to rationally tune the binding properties of biomolecular receptors
Ricci, F., Vallée-Bélisle, A., Simon, A. J., Porchetta, A., & Plaxco, K. W. (2016). Accounts of Chemical Research, 49(9), 1884-1892.
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Electronic control of DNA-based nanoswitches and nanodevices
Ranallo, S., Amodio, A., Idili, A., Porchetta, A., & Ricci, F. (2016). Chemical Science, 7(1), 66-71.
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Controlling hybridization chain reactions with pH
Idili, A., Porchetta, A., Amodio, A., Vallée-Bélisle, A., & Ricci, F. (2015). Nano Letters, 15(8), 5539-5544.
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General strategy to introduce pH-induced allostery in DNA-based receptors to achieve controlled release of ligands
Porchetta, A., Idili, A., Vallée-Bélisle, A., & Ricci, F. (2015). Nano Letters, 15(7), 4467- 4471.
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A general approach to the design of allosteric, transcription factor-regulated DNAzymes
Adornetto, G., Porchetta, A., Palleschi, G., Plaxco, K. W., & Ricci, F. (2015). Chemical Science, 6(7), 3692-3696.
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Rational design of pH-controlled DNA strand displacement
Amodio, A., Zhao, B., Porchetta, A., Idili, A., Castronovo, M., Fan, C., & Ricci, F. (2014). Journal of the American Chemical Society, 136(47), 16469-16472.
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Photoinduced electron transfer through peptide-based self-assembled monolayers chemisorbed on gold electrodes: Directing the flow-in and flow-out of electrons through peptide helices
Venanzi, M., Gatto, E., Caruso, M., Porchetta, A., Formaggio, F., & Toniolo, C. (2014). Journal of Physical Chemistry A, 118(33), 6674-6684.
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Allosterically tunable, DNA-based switches triggered by heavy metals
Porchetta, A., Vallée-Bélisle, A., Plaxco, K. W., & Ricci, F. (2013). Journal of the American Chemical Society, 135(36), 13238- 13241.
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Using distal-site mutations and allosteric inhibition to tune, extend, and narrow the useful dynamic range of aptamer-based sensors
Porchetta, A., Vallée-Bélisle, A., Plaxco, K. W., & Ricci, F. (2012). Journal of the American Chemical Society, 134(51), 20601-20604.
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Rational design of allosteric inhibitors and activators using the population-shift model: In vitro validation and application to an artificial biosensor
Ricci, F., Vallée-Bélisle, A., Porchetta, A., & Plaxco, K. W. (2012). Journal of the American Chemical Society, 134(37), 15177-15180.
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Re-engineering electrochemical biosensors to narrow or extend their useful dynamic range
Kang, D., Vallée-Bélisle, A., Porchetta, A., Plaxco, K. W., & Ricci, F. (2012). Angewandte Chemie - International Edition, 51(27), 6717-6721.
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Playing with peptides: How to build a supramolecular peptide nanostructure by exploiting Helix…Helix macrodipole interactions
Gatto, E., Porchetta, A., Scarselli, M., De Crescenzi, M., Formaggio, F., Toniolo, C., & Venanzi, M. (2012). Langmuir, 28(5), 2817-2826.
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Spectroscopy and electrochemistry of peptide-based self-assembled monolayers
Caruso, M., Porchetta, A., Gatto, E., Venanzi, M., Crisma, M., Formaggio, F., & Toniolo, C. (2012)
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Probe accessibility effects on the performance of electrochemical biosensors employing DNA monolayers
Biagiotti, V., Porchetta, A., Desiderati, S., Plaxco, K. W., Palleschi, G., & Ricci, F. (2012). Analytical and Bioanalytical Chemistry, 402(1), 413-421.
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Photocurrent generation through peptide-based self-assembled monolayers on a gold surface: Antenna and junction effects
Gatto, E., Caruso, M., Porchetta, A., Toniolo, C., Formaggio, F., Crisma, M., & Venanzi, M. (2011). Journal of Peptide Science, 17(2), 124-131.
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Conformational effects on the electron-transfer efficiency in peptide foldamers based on α,α- disubstituted glycyl residues
Gatto, E., Porchetta, A., Stella, L., Guryanov, I., Formaggio, F., Toniolo, C., Kaptein, B., Broxterman, Q.B., & Venanzi, M. (2008). Chemistry and Biodiversity, 5(7), 1263-1278.
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